Abstract: From December 2019 to October 2020, macrobenthos samples in three habitats of Phragmites communis, Sonneratia apetala and bare flat in the Nansha Wetland of Guangzhou were collected, and the secondary productivity and P/B value (the ratio of secondary production to biomass) were calculated and analyzed to reveal the spatiotemporal characteristics of macrobenthos. The results indicated significant differences in the secondary productivity and the P/B ratio among the macrobenthic communities across different habitats. The average annual secondary production of macrobenthos in the P. communis weland, the S. apetala wetland and the bare flat were 36.59 g/(m²·a), 13.31 g/(m²·a) and 4.56 g/(m²·a), respectively, and the P/B values were 1.24, 1.20 and 0.84, respectively. The secondary production of macrobenthos in the P. communis wetland was the highest, followed by that in the S. apetala wetland, and the lowest in the bare flat. A two-way analysis of variance indicated that the secondary production and P/B ratios of macrobenthos differed significantly among the three habitats (F=6.50, p<0.01), but no significant differences were observed among different seasons (p>0.05). Correlation analysis indicated that the secondary production of macrobenthos was significantly negatively correlated with soil pH (p<0.05), and the P/B ratio was significantly negatively correlated with soil salinity and electrical conductivity (p<0.05).