Abstract: The 33 national wetland parks on both sides of the Shandong section of the Yellow River are important components of wetland ecosystem in the lower reaches of the Yellow River. And their ecosystem service function can affect regional ecological security and development quality. Based on the planning of national wetland parks, relevant statistical data, and field investigations, combined with the distribution characteristics, composition structure, and ecological functions of ecosystems, the equivalent factor method, correlation analysis, and spatial analysis methods were used to evaluate the ecosystem service value, and analysis the spatial changes of these parks. The results showed that the total area of 33 national wetland parks was 32 447.68 hm², with a total wetland area of 25 465.72 hm² and an average wetland rate of 76.05%. The total value of ecosystem services of 33 national wetland parks ranged from 17 million yuan to 269 million yuan, with Shandong Fulong Lake National Wetland Park in Shan County having the highest value and Yuema River National Wetland Park in Laoling having the lowest value. The ecosystem service value per unit area of the Yellow River Ancient Path National Wetland Park in Cao County was the highest. The proportion of wetland ecosystem service value in the total service value of national wetland parks was between 73.92% and 99.65%. The ecosystem service value of the national wetland Park decreased slightly downstream the Yellow River, and was higher in the southeast and lower in the northwest. The ecosystem service value is closely linked to the area and wetland rate of national wetland parks.